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Nanomaterials with dual immunomodulatory functions for synergistic therapy of br...
Time:2023/6/28 15:08:20
A long-standing paucity of effective therapies results in the poor outcomes of triple-negative breast cancer brain metastases. Immunotherapy has made progress in the treatment of tumors, but limited by the non-immunogenicity of tumors and strong immunosuppres...
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Gradient Tumor Microenvironment-Promoted Penetrating Micelles for Hypoxia Relief...
Time:2023/6/14 23:35:59
Recently, we developed a hypoxia-responsive nanomicellar drug delivery system for pancreatic cancer microenvironment, which can respond to the hypoxic microenvironment of pancreatic tumors and enhance the penetration of the material into the internal tumor wh...
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ROS/Electro Dual-Reactive Nanogel for Targeting Epileptic Foci to Remodel Aberra...
Time:2023/4/13 16:27:00
We have recently reported a hydrogel nanoparticle drug delivery system, or namely nanogel, which is hopeful to address several problems facing the currently prevalent anti-epileptic drug therapies in epileptic treatment. A reactive oxygen species-res...
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Transcytosis Mediated Deep Tumor Penetration for Enhanced Chemotherapy and Immun...
Time:2023/4/7 15:56:33
Recently, our group has developed a versatile drug delivery system that can trigger transcytosis. The delivery system can efficiently deliver chemotherapy drugs to the deep tumor, regulate the microenvironment, and activate the anti-PDAC immune response. The ...
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Stimuli-Responsive Drug Delivery Systems Triggered by Intracellular or Subcellul...
Time:2023/3/11 13:23:44
Drug delivery systems (DDSs) triggered by local microenvironment represents the state-of-art of nanomedicine design, where the triggering hallmarks at intracellular and subcellular levels could be employed to exquisitely recognize the diseased sites, reduce s...
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