1. Zhao ZH, Zhou JY, Li XW, Zhang TY, Tian ZH, Sun T, Jiang C*.Manganese-based virus-mimicking nanomedicine with triple immunomodulatory functions inhibits breast cancer brain metastasis. Biomaterials. 2025;123262.
https://www.sciencedirect.com/science/article/pii/S0142961225001814
2. Fang MZ, Su BY, Zhang SL, Li FX, Guo Yun, Chen QJ, Wu YX, Liu HY, Jiang C*, Sun T*. Engineered Intelligent Microenvironment Responsive Prodrug Conjugates Navigated by Bioinspired Lipoproteins for Reversing Liver Fibrosis. Small Methods. 2025, 2402247.
https://onlinelibrary.wiley.com/doi/10.1002/smtd.202402247
3. You HY, Zhang SL, Zhang YW, Chen QJ, Wu YX, Zhou Z, Zhao ZH, Su BY, Li XW, Guo Y, Chen Y, Tang WY, Liu B, Fan HR, Geng S, Fang MZ, Li FX, Liu GN, Jiang C*, Sun T*. Engineered Bacterial Outer Membrane Vesicles-Based Doxorubicin and CD47-siRNA Co-Delivery Nanoplatform Overcomes Immune Resistance to Potentiate the Immunotherapy of Glioblastoma. Advanced Materials. 2025, 2418053.
https://advanced.onlinelibrary.wiley.com/doi/full/10.1002/adma.202418053
4. Su BY, Chen QJ, Li XW, Fang MZ, Wang Y, Song HL, You HY, Zhou Z, Wu YX, Zhao ZH, Chen Y, Fan HR, Li CF, Jiang C*, Sun T*. A Methionine Allocation Nanoregulator for the Suppression of Cancer Stem Cells and Support to the Immune Cells by Epigenetic Regulation. Advanced Science. 2025, 2415207.
https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202415207
5. Zhang SL, You HY, Fan HR, Chen Y, Song HL, Zhao ZH, Chen QJ, Wang Y, Tian ZH, Wu YX, Zhou Z, Guo Y, Su BY, Li XW, Jia R, Fang MZ, Jiang C*, Sun T*. Transcytosis-Triggering Nanoparticles for Overcoming Stromal Barriers and Reversing Immunosuppression in Pancreatic Cancer Combinatorial Therapy. Nano Letters. 2025;25(7):2949–2959
https://pubs.acs.org/doi/10.1021/acs.nanolett.4c06372
6. Wang Y, Chen QJ, Luo YF, Qu YQ, Li XW, Song HL, Li CF, Zhang YW, Sun T, Jiang C*. Metabolic Nanoregulators Induce Ferroptosis and Change Metabolite Flow to Reverse Immunosuppressive Tumor Microenvironment. ACS Nano. 2024;18(51):34996–35012.
https://pubs.acs.org/doi/10.1021/acsnano.4c13425
7. Li YY, Wu YK, Gao SH, Sun T*, Jiang C. PROTAC delivery in tumor immunotherapy: Where are we and where are we going? Journal of Controlled Release. 2025;378:116–144
https://doi.org/10.1016/j.jconrel.2024.11.076
8. Song HL, Chen HY, Chen QJ, Fan HR, Li CF, Wang Y, Zhang SL, Li XW, Su BY, Sun T, Jiang C*. Size and Charge Dual-Switchable Nanoparticles for Achieving Chemosensitization and Immune Infiltration against Pancreatic Ductal Adenocarcinoma. Advanced Functional Materials. 2024, 2411643.
https://doi.org/10.1002/adfm.202411643
9. Li CF, Chen QJ, Jiang C*. Intelligent micelles for on-demand drug delivery targeting extracellular matrix of pancreatic cancer. Journal of Controlled Release. 2024;373:879-889.
https://www.sciencedirect.com/science/article/pii/S0168365924005169?via%3Dihub
10. Liu PX, Zhang TY, Wu YX, Chen QJ, Sun T, Jiang C*. A Peptide-Drug Conjugate-Based Nanoplatform for Immunometabolic Activation and In Situ Nerve Regeneration in Advanced-Stage Alzheimer's Disease. Advanced Materials. 2024;2407829.
https://onlinelibrary.wiley.com/doi/10.1002/adma.202408729
11. You HY, Geng S, Li SK, Imani M, Brambilla D, Sun T*, Jiang C. Recent advances in biomimetic strategies for the immunotherapy of glioblastoma. Biomaterials. 2024;122694.
https://doi.org/10.1016/j.biomaterials.2024.122694
12. Li XW, Guo Q, Chen QJ, Chu YC, Zhang YW, Chen HY, Zhao ZH, Wang Y, Luo YF, Li CF, You HY, Song HL, Su BY, Jalili K, Sun T, Jiang C*. Reconciling the Cooperative–Competitive Patterns among Tumor and Immune Cells for Triple-Negative Breast Cancer Treatment Using Multimodule Nanocomplexes. Advanced Materials. 2024;2312219.
https://onlinelibrary.wiley.com/doi/10.1002/adma.202312219
13. Su BY, Li SK, Geng S, Brambilla D, Sun R, Sun T*, Jiang C. Therapeutic regulation of epigenetics in cancer treatment through drug delivery systems. Nano Today. 2024;102251.
https://www.sciencedirect.com/science/article/pii/S1748013224001063?via%3Dihub
14. Li XW, Sun T*, Jiang C*. Intelligent Delivery Systems in Tumor Metabolism Regulation: Exploring the Path Ahead. Advanced Materials. 2024;2309582.
https://onlinelibrary.wiley.com/doi/10.1002/adma.202309582
15. Zhao ZH, Chen Y, Sun T, Jiang C*. Nanomaterials for brain metastasis. Journal of Controlled Release. 2024;365:833-847.
https://www.sciencedirect.com/science/article/pii/S016836592300785X?dgcid=coauthor
16. Li C, Wu YX, Chen QJ, Luo YF, Liu PX, Zhou Z, Zhao ZH, Zhang TY, Su BY, Sun T, Jiang C*. Pleiotropic Microenvironment Remodeling Micelles for Cerebral Ischemia-Reperfusion Injury Therapy by Inhibiting Neuronal Ferroptosis and Glial Overactivation. ACS Nano. 2023;17(18):18164-18177.
https://pubs.acs.org/doi/full/10.1021/acsnano.3c05038
17. Zhao ZH, Li CF, Zhang YW, Li C, Chu YC, Li XW, Liu PX, Chen HY, Wang Y, Su BY, Chen QJ, Sun T, Jiang C*. Nanomaterials with dual immunomodulatory functions for synergistic therapy of breast cancer brain metastases. Bioactive Materials. 2023;27:474-487.
https://doi.org/10.1016/j.bioactmat.2023.04.021
18. Luo YF, Li C, Zhang YW, Liu PX, Chen HY, Zhao ZH, Wang Y, Zhou Z, Song HL, Su BY, Li CF, Li XW, Zhang TY, You HY, Wu YX, Tian ZH, Zhang SL, Guo Y, Fan HR, Chen QJ, Jiang C*, Sun T*. Gradient tumor microenvironment-promoted penetrating micelles for hypoxia relief and immunosuppression reversion in pancreatic cancer treatment. Acta Biomaterialia. 2023;167:387-400.
https://doi.org/10.1016/j.actbio.2023.05.047
19. Sun T*, Chen QJ, Zhou Z, Li C, Yu T, Jiang C*. A chemiluminescent reporter assisted by in-situ neutrophils for imaging O2·- at inflammatory sites. Journal of Controlled Release. 2023;358:382-397.
https://doi.org/10.1016/j.jconrel.2023.04.035
20. Zhou Z, Li KY, Guo Y, Liu PX, Chen QJ, Fan HR, Sun T, Jiang C*. ROS/Electro Dual-Reactive Nanogel for Targeting Epileptic Foci to Remodel Aberrant Circuits and Inflammatory Microenvironment. ACS Nano. 2023;17(8):7847-7864.
https://doi.org/10.1021/acsnano.3c01140
21. Chen HY, Song HL, Luo YF, Li CF, Wang Y, Liu J, Luo FF, Fan HR, Li XW, Sun T*, Jiang C*. Transcytosis Mediated Deep Tumor Penetration for Enhanced Chemotherapy and Immune Activation of Pancreatic Cancer. Advanced Functional Materials. 2023;2214937.
https://doi.org/10.1002/adfm.202214937
22. Sun T, Jiang C*. Stimuli-Responsive Drug Delivery Systems Triggered by Intracellular or Subcellular Microenvironments. Advanced Drug Delivery Reviews. 2023;114773.
https://www.sciencedirect.com/science/article/pii/S0169409X23000881
23. Liu PX, Zhang TY, Li C, Zhang YW, Zhou Z, Zhao ZH, Chen QJ, Sun T, Jiang C*. Bioinspired nanoerythrocytes for metabolic microenvironment remodeling and long-term prognosis promoting of acute ischemic stroke. Nano Today. 2023;101806.
https://doi.org/10.1016/j.nantod.2023.101806
24. Chu YC, Su BY, Luo YF, Li C, Zhang YW, Liu PX, Chen HY, Maciej S, Jiang C*, Sun T*. Compound Nanoemulsion Combined with Differentiation/ Cytotoxicity Drugs for Modulating Breast Cancer Stemness. Molecular Pharmaceutics. 2023;20(3):1591-1598.
https://doi.org/10.1021/acs.molpharmaceut.2c00784
25. Zhang YW, You HY, Zhao ZH, Luo YF, Li C, Liu PX, Chen HY, Wang Y, Zhou Z, Sun T*, Jiang C*. Transformable “Tubulin Traps” Interfere with Mitochondrial Autophagy and Promote the Elimination of Glioblastoma. Advanced Functional Materials. 2023;2209216.
https://doi.org/10.1002/adfm.202209216
26. Zhou Z, Li KY, Chu YC, Li C, Zhang TY, Liu PX, Sun T, Jiang C*. ROS-removing nano-medicine for navigating inflammatory microenvironment to enhance anti-epileptic therapy. Acta Pharmaceutica Sinica B. 2023;13(3):1246-1261.
https://doi.org/10.1016/j.apsb.2022.09.019
27. Wang Y, Chen QJ, Song HL, Zhang YW, Chen HY, Liu PX, Sun T, Jiang C*. A Triple Therapeutic Strategy with Antiexosomal Iron Efflux for Enhanced Ferroptosis Therapy and Immunotherapy. Small. 2022;2201704.
https://doi.org/10.1002/smll.202201704
28. Zhao ZH, Zhang YJ, Li C, Li XW, Chu YC, Guo Q, Zhang YW, Xia WY, Liu PX, Chen HY, Wang Y, Li CF, Sun T, Jiang C*. Microenvironment-tailored micelles restrain carcinoma-astrocyte crosstalk for brain metastasis. Journal of Controlled Release. 2022;349:520-532.
https://doi.org/10.1016/j.jconrel.2022.07.009
29. Chu YC, Luo YF, Su BY, Li C, Guo Q, Zhang YW, Liu PX, Chen HY, Zhao ZH, Zhou Z, Wang Y, Jiang C*, Sun T*. A neutrophil-biomimic platform for eradicating metastatic breast cancer stem-like cells by redox microenvironment modulation and hypoxia-triggered differentiation therapy. Acta Pharmaceutica Sinica B. 2022;13(1):298-314.
https://doi.org/10.1016/j.apsb.2022.05.027
30. Chen HY, Sun T, Jiang C*. Extracellular vesicle-based macromolecule delivery systems in cancer immunotherapy. Journal of Controlled Release. 2022;348:572-589.
https://doi.org/10.1016/j.jconrel.2022.06.014
31. Chen HY, Guo Q, Chu YC, Li C, Zhang YW, Liu PX, Zhao ZH, Wang Y, Luo YF, Zhou Z, Zhang TY, Song HL, Li XW, Li CF, Su BY, You HY, Sun T, Jiang C*. Smart hypoxia-responsive transformable and charge-reversible nanoparticles for the deep penetration and tumor microenvironment modulation of pancreatic cancer. Biomaterials. 2022;121599.
https://doi.org/10.1016/j.biomaterials.2022.121599
32. Xia WY, Li C, Chen QJ, Huang JC, Zhao ZH, Liu PX, Xu K, Li L, Hu FY, Zhang SJ, Sun T, Jiang C*, Zhao C*. Intravenous route to choroidal neovascularization by macrophage-disguised nanocarriers for mTOR modulation. Acta Pharmaceutica Sinica B. 2022;12(5):2506-2521.
https://doi.org/10.1016/j.apsb.2021.10.022
33. Liu PX, Jiang C*. Brain-Targeting Drug Delivery Systems. Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology. 2022;e1818
https://doi.org/10.1002/wnan.1818
34. Chen QJ, Wang QB, Wang Y, Chu YC, Luo YF, You HY, Su BY, Li C, Guo Q, Sun T*, Jiang C*. Penetrating Micelle for Reversing Immunosuppression and Drug Resistance in Pancreatic Cancer Treatment. Small. 2022;2107712.
https://doi.org/10.1002/smll.202107712
35. Song HL, Jiang C*. Recent advances in targeted drug delivery for the treatment of pancreatic ductal adenocarcinoma. Expert Opinion on Drug Delivery. 2022;19(3):281-301.
https://doi.org/10.1080/17425247.2022.2045943
36. Wang Y, Sun T, Jiang C*. Nanodrug delivery systems for ferroptosis-based cancer therapy. Journal of Controlled Release. 2022;344:289-301.
https://doi.org/10.1016/j.jconrel.2022.01.034
37. Zhang YW, You HY, Wang YB, Chen QJ, Chu YC, Li C, Zhou WX, Chen HY, Liu PX, Wang Y, Zhao ZH, Zhou Z, Luo LY, Li XW, Zhang TY, Song HL, Li CF, Su BY, Sun T, Bi YK*, Yu L*, Jiang C*. A Micro-Environment Regulator for Filling the Clinical Treatment Gap after a Glioblastoma Operation. Advanced Healthcare Materials. 2022;2101578.
https://doi.org/10.1002/adhm.202101578
38. Zhou WX, Chen XL, Zhou Y, Shi S, Liang C, Yu XJ, Chen HY, Guo Q, Zhang YW, Liu PX, Li C, Chu YC, Luo YF, Wang Y, Zhou Z, Zhao ZH, Chen QJ, Sun T, Jiang C*. Exosomes derived from immunogenically dying tumor cells as a versatile tool for vaccination against pancreatic cancer. Biomaterials. 2022;121599.
https://doi.org/10.1016/j.biomaterials.2021.121306.
39. Guo Q, Li XW, Zhou WX, Chu YC, Chen QJ, Zhang YW, Li C, Chen HY, Liu PX, Zhao ZH, Wang Y, Zhou Z, Luo YF, Li CF, You HY, Song HL, Su BY, Zhang TY, Sun T, Jiang C*. Sequentially Triggered Bacterial Outer Membrane Vesicles for Macrophage Metabolism Modulation and Tumor Metastasis Suppression. ACS Nano. 2021;15(8):13826-13838.
https://doi.org/10.1021/acsnano.1c05613
40. Li C, Zhao ZH, Luo YF, Ning TT, Liu PX, Chen QJ, Chu YC, Guo Q, Zhang YW, Zhou WX, Chen HY, Zhou Z, Wang Y, Su BY, You HY, Zhang TY, Li XW, Song HL, Li CF, Sun T, Jiang C*. Macrophage-Disguised Manganese Dioxide Nanoparticles for Neuroprotection by Reducing Oxidative Stress and Modulating Inflammatory Microenvironment in Acute Ischemic Stroke. Advanced Science. 2021; 2101526.
https://doi.org/10.1002/advs.202101526
41. Sun T, Zhang GP, Ning TT, Chen QJ, Chu YC, Luo YF, You HY, Su BY, Li C, Guo Q, Jiang C*. A Versatile Theranostic Platform for Colorectal Cancer Peritoneal Metastases: Real-Time Tumor-Tracking and Photothermal-Enhanced Chemotherapy. Advanced Science. 2021;2102256.
https://doi.org/10.1002/advs.202102256
42. Li C, Sun T, Jiang C*. Recent advances in nanomedicines for the treatment of ischemic stroke. Acta Pharmaceutica Sinica B. 2021;11(7):1767-1788.
https://doi.org/10.1016/j.apsb.2020.11.019
43. Liu PX, Zhang TY, Chen QJ, Li C, Chu YC, Guo Q, Zhang YJ, Zhou WX, Chen HY, Zhou Z, Wang Y, Zhao ZH, Luo YF, Li XW, Song HL, Su BY, Li CF, Sun T, Jiang C*. Biomimetic Dendrimer–Peptide Conjugates for Early Multi‐Target Therapy of Alzheimer's Disease by Inflammatory Microenvironment Modulation. Advanced Materials. 2021;2100746.
https://doi.org/10.1002/adma.202100746
44. Chen QJ, Sun T, Jiang C*. Recent Advancements in Nanomedicine for ‘Cold’ Tumor Immunotherapy. Nano-Micro Letters. 2021;13(1):92.
https://doi.org/10.1007/s40820-021-00622-6
45. Guo Q, Chen QJ, Zhang YJ, Zhou WX, Li XW, Li C, Zhang YW, Chen HY, Liu PX, Chu YC, Sun T, Jiang C*. Click-Nucleic-Acid-Containing Codelivery System Inducing Collapse of Cellular Homeostasis for Tumor Therapy through Bidirectional Regulation of Autophagy and Glycolysis. ACS Applied Materials & Interfaces. 2020;12(52):57757-57767.
https://doi.org/10.1021/acsami.0c18361
46. Zhang YW, Jiang C*. Postoperative cancer treatments: In-situ delivery system designed on demand. Journal of Controlled Release. 2021;330:554-564.
https://doi.org/10.1016/j.jconrel.2020.12.038
47. Zhou WX, Zhou Y, Chen XL, Ning TT, Chen HY, Guo Q, Zhang YW, Liu PX, Zhang YJ, Li C, Chu YC, Sun T, Jiang C*. Pancreatic cancer-targeting exosomes for enhancing immunotherapy and reprogramming tumor microenvironment. Biomaterials. 2021;120546.
https://doi.org/10.1016/j.biomaterials.2020.120546
48. Chen QJ, He YQ, Wang Y, Li C, Zhang YJ, Guo Q, Zhang YW, Chu YC, Liu PX, Chen HY, Zhou Z, Zhou WX, Zhao ZH, Li XM, Sun T, Jiang C*. Penetrable Nanoplatform for “Cold” Tumor Immune Microenvironment Reeducation. Advanced Science. 2020;2000411.
https://doi.org/10.1002/advs.202000411
49. Sun T, Ding XH, Wang XF, Zhang K, Zhang GP, Liang DH, Yu KJ, Chu YC, Chen QJ, Jiang C*. Carry-On Nitric-Oxide Luggage for Enhanced Chemotherapeutic Efficacy. Nano Letters. 2020;20(7):5275-5283.
https://doi.org/10.1021/acs.nanolett.0c01532
50. Li C, Xie ZC, Chen QJ, Zhang YJ, Chu YC, Guo Q, Zhou WX, Zhang YW, Liu PX, Chen HY, Jiang C*, Sun KY*, Sun T*. Supramolecular Hunter Stationed on Red Blood Cells for Detoxification Based on Specific Molecular Recognition. ACS Nano. 2020;14(4):4950-4962.
https://doi.org/10.1021/acsnano.0c01119
51. Sun T, Zhang GP, Guo ZY, Chen QJ, Zhang YJ, Chu YC, Guo Q, Li C, Zhou WX, Zhang YW, Liu PX, Chen HY, Yu HJ, Jiang LP, Jiang C*. Co-delivery of Cu(I) chelator and chemotherapeutics as a new strategy for tumor theranostic. Journal of Controlled Release. 2020;321:483-496.
https://doi.org/10.1016/j.jconrel.2020.02.023
52. Guo Q, He X, Li C, He Y, Peng Y, Zhang Y, Lu Y, Chen X, Zhang Y, Chen Q, Sun T, Jiang C*. Dandelion‐Like Tailorable Nanoparticles for Tumor Microenvironment Modulation. Advanced Science. 2019;1901430.
https://doi.org/10.1002/advs.201901430
53. Sun T, Zhang GP, Wang QB, Guo ZY, Chen QJ, Chen XL, Lu YF, Zhang Y, Zhang Y, Guo Q, Gao X, Cheng YZ, Jiang C*. Pre-blocked molecular shuttle as an in-situ real-time theranostics. Biomaterials. 2019;204:46-58.
https://doi.org/10.1016/j.biomaterials.2019.02.019
54. Liu LS, Chen QJ, Ruan CH, Chen XL, He X, Zhang Y, Zhang YJ, Lu YF, Guo Q, Zhou WX, Li C, Sun T, Jiang C*. Nano-engineered lymphocytes for alleviating suppressive tumor immune microenvironment. Applied Materials Today. 2019;16:273-279.
https://doi.org/10.1016/j.apmt.2019.06.009
55. Zhang Y, Zhang YJ, Guo Q, Guo ZY, Chen XL, Liu LS, Li C, Chen QJ, He X, Lu YF, Sun T, Huang YZ, Jiang C*. Trained Macrophage Bioreactor for Penetrating Delivery of Fused Antitumor Protein. ACS Applied Materials & Interfaces. 2019;11(26):23018-23025.
https://doi.org/10.1021/acsami.9b06097
56. Chen XL，Zhou WX, Chen QJ, Sun T, Lu YF, Zhang YJ, Guo Q, Li C, Zhang Y, Liang C, Shi S, Yu XJ, Jiang C*. Codelivery Nanosystem Targeting the Deep Microenvironment of Pancreatic Cancer. Nano Letters. 2019;19(6):3527-3534.
https://pubs.acs.org/doi/full/10.1021/acs.nanolett.9b00374
57. Lu YF, Li C, Chen QJ, Liu PX, Guo Q, Zhang Y, Chen XL, Zhang YJ, Zhou WX, Liang DH, Zhang YW, Sun T, Lu WG*, Jiang C*. Microthrombus‐Targeting Micelles for Neurovascular Remodeling and Enhanced Microcirculatory Perfusion in Acute Ischemic Stroke. Advanced Materials. 2019;1808361.
https://onlinelibrary.wiley.com/doi/full/10.1002/adma.201808361
58. Guo Q, Li C, Zhou WX, Chen XL, Zhang Y, Lu YF, Zhang YJ, Chen QJ, Liang DH, Sun T, Jiang C*. GLUT1-mediated effective anti-miRNA21 pompon for cancer therapy. Acta Pharmaceutica Sinica B. 2019;9(4):832–842.
https://www.sciencedirect.com/science/article/pii/S221138351831178X?via%3Dihub
59. Chen QJ, Liu LS, Lu YF, Chen XL, Zhang YJ, Zhou WX, Guo Q, Li C, Zhang YW, Zhang Y, Liang DH, Sun T, Jiang C*. Tumor Microenvironment‐Triggered Aggregated Magnetic Nanoparticles for Reinforced Image‐Guided Immunogenic Chemotherapy. Advanced Science. 2019;1802134.
https://onlinelibrary.wiley.com/doi/10.1002/advs.201802134
60. Zhang YJ, Zhu X, Chen XL, Chen QJ, Zhou WX, Guo Q, Lu YF, Li C, Zhang Y, Liang DH, Sun T, Wei XB, Jiang C*. Activated Platelets-Targeting Micelles with Controlled Drug Release for Effective Treatment of Primary and Metastatic Triple Negative Breast Cancer. Advanced Functional Materials. 2019;1806620.
https://onlinelibrary.wiley.com/doi/full/10.1002/adfm.201806620
61. Lu YF, Guo ZY, Zhang YJ, Li C, Zhang Y, Guo Q, Chen QJ, Chen XL, He X, Liu LS, Ruan CH, Sun T, Ji B, Lu WG, Jiang C*. Microenvironment remodeling micelles for Alzheimer’s disease therapy by early modulation of activated microglia. Advanced Science. 2018;1801586.
https://onlinelibrary.wiley.com/doi/full/10.1002/advs.201801586
62. He X, Cai KM, Zhang Y, Lu YF, Guo Q, Zhang YJ, Liu LS, Ruan CH, Chen QJ, Chen XL, Li C, Sun T, Cheng JJ*, Jiang C*. Dimeric Prodrug Self-Delivery Nanoparticles with Enhanced Drug Loading and Bioreduction Responsiveness for Targeted Cancer Therapy. ACS Appl. Mater. Interfaces. 2018;10(46):39455–39467.
https://pubs.acs.org/doi/full/10.1021/acsami.8b09730
63. He X, Chen XL, Liu LS, Zhang Y, Lu YF, Zhang YJ, Chen QJ, Ruan CH, Guo Q, Li C, Sun T, Jiang C*. Sequentially triggered nanoparticles with tumor penetration and intelligent drug release for pancreatic cancer therapy. Advanced Science. 2018;1701070.
https://onlinelibrary.wiley.com/doi/full/10.1002/advs.201701070
64. Zhang Y, Cai KM, Li C, Guo Q, Chen QJ, He X, Liu LS, Zhang YJ, Lu YF, Chen XL, Sun T, Huang YZ, Cheng JJ, Jiang C*. Macrophage membrane-coated nanoparticles for tumor-targeted chemotherapy. Nano Letters. 2018;18(3):1908-1915.
https://pubs.acs.org/doi/full/10.1021/acs.nanolett.7b05263
65. Zhang YJ, Guo ZY, Cao ZL, Zhou WX, Zhang Y, Chen QJ, Lu YF, Chen XL, Guo Q, Li C, Liang DH, Sun T, Jiang C*. Endogenous albumin-mediated delivery of redox responsive micelles for targeted cancer therapy. Biomaterials. 2018;183:243-257.
https://www.sciencedirect.com/science/article/pii/S0142961218304174
66. Chen XL, Wang QB, Liu LS, Sun T, Wenxi Zhou, Chen QJ, Lu YF, He X, Zhang Y, Zhang YJ, Ruan CH, Guo Q, Chao Li, Jiang C*. Double-sided effect of tumor microenvironment on platelets targeting nanoparticles. Biomaterials. 2018;183:258-267.
https://www.sciencedirect.com/science/article/pii/S0142961218304745
67. Sun T, Zhang GP, Wang QB, Chen QJ, Chen XL, Lu YF, Liu LS, Zhang Y, He X, Ruan CH, Zhang YJ, Guo Q, Jiang C*. A targeting theranostics nanomedicine as an alternative approach for hyperthermia perfusion. Biomaterials. 2018;183:268-279.
https://www.sciencedirect.com/science/article/pii/S0142961218302631
68. He X, Zhang JX, Li C, Zhang Y, Lu YF, Zhang YJ, Liu LS, Ruan CH, Chen QJ, Chen XL, Guo Q, Sun T, Cheng JJ*, Jiang C*. Enhanced bioreduction-responsive diselenide-based dimeric prodrug nanoparticles for triple negative breast cancer therapy. Theranostics. 2018;8(18):4884-4897.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217054/
69. Liu LS, Chen QJ, Ruan CH, Chen XL, Zhang Y, He X, Zhang YJ, Lu YF, Guo Q, Sun T, Wang H*, Jiang C*. Platinum-based nanovectors engineered with immune-modulating adjuvant for inhibiting tumor growth and promoting immunity. Theranostics, 2018;8(11):2974-2987.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996371/
70. Ruan CH, Liu LS, Wang QB, Chen XL, Chen QJ, Lu YF, Zhang Y, He X, Zhang YJ, Guo Q, Sun T, Jiang C*. Reactive oxygen species-biodegradable gene carrier for the targeting therapy of breast cancer. ACS Applied Materials & Interfaces. 2018;10(12):10398-10408.
https://pubs.acs.org/doi/full/10.1021/acsami.8b01712
71. Zhang YJ, Sun T, Jiang C*. Biomacromolecules as carriers in drug delivery and tissue engineering. Acta Pharmaceutica Sinica B. 2018;8(1):34-50.
https://www.sciencedirect.com/science/article/pii/S2211383517302812
72. Ruan CH, Liu LS, Lu YF, Zhang Y, He X, Chen XL, Zhang YJ, Chen QJ, Guo Q, Sun T*, Jiang C*. Substance P-modified human serum albumin nanoparticles loaded with paclitaxel for targeted therapy of glioma. Acta Pharmaceutica Sinica B. 2018;8(1):85-96.
https://www.sciencedirect.com/science/article/pii/S2211383517302824
73. Zhang YJ, Lu YF, Zhang Y, He X, Chen QJ, Liu LS, Chen XL, Ruan CH, Sun T, Jiang C*. Tumor-Targeting Micelles Based on Linear-Dendritic PEG-PTX8 Conjugate for Triple Negative Breast Cancer Therapy. Molecular Pharmaceutics. 2017;14(10):3409-3421.
https://pubs.acs.org/doi/full/10.1021/acs.molpharmaceut.7b00430
74. Sun T, Jiang XT, Wang QB, Chen QJ, Lu YF, Liu LS, Zhang Y, He X, Ruan CH, Zhang YJ, Guo Q, Liu YH, Jiang C*. Substance P Mediated DGLs Complexing with DACHPt for Targeting Therapy of Glioma. ACS Applied Materials & Interfaces. 2017;9(40):34603-34617.
https://pubs.acs.org/doi/full/10.1021/acsami.7b05997
75. Sun T, Wang QB, Bi YK, Chen XL, Liu LS, Ruan CH, Zhao ZF, C. Jiang*. Supramolecular amphiphiles based on cyclodextrin and hydrophobic drugs, Journal of Materials Chemistry B. 2017;5(14):2644-2654.
https://doi.org/10.1039/C6TB03272A
76. Liu LS, Bi YK, Zhou MR, Chen XL, He X, Zhang YJ, Sun T, Ruan CH, Chen QJ, Wang H, Jiang C*. Biomimetic Human Serum Albumin Nanoparticle for Efficiently Targeting Therapy to Metastatic Breast Cancers. ACS Applied Materials & Interfaces. 2017;9(8):7424-7435.
https://pubs.acs.org/doi/full/10.1021/acsami.6b14390
77. Zhang Y, Guo Q, An S, Lu YF, Li JF, He X, Liu LS, Zhang YJ, Sun T, Jiang C*. ROS-Switchable Polymeric Nanoplatform with Stimuli-Responsive Release for Active Targeted Drug Delivery to Breast Cancer. ACS Applied Materials & Interfaces. 2017;9(14):12227-12240.
https://pubs.acs.org/doi/full/10.1021/acsami.6b16815
78. Liu Y, An S, Li J, Kuang YY, He X, Guo YB, Ma HJ, Zhang Y, Ji B, Jiang C*. Brain-targeted co-delivery of therapeutic gene and peptide by multifunctional nanoparticles in Alzheimer's disease mice. Biomaterials. 2016;80:33-45.
https://www.sciencedirect.com/science/article/pii/S0142961215009709
79. An S, Lu XH, Zhao WL, Sun T, Zhang Y, Lu YF, Jiang C*. Amino Acid Metabolism Abnormity and Microenvironment Variation Mediated Targeting and Controlled Glioma Chemotherapy. Small. 2016;12(40):5633-5645.
https://onlinelibrary.wiley.com/doi/full/10.1002/smll.201601249
80. Kuang YY, Jiang XT, Zhang Y, Lu YF, Ma HJ, Guo YB, Zhang YJ, An S, Li JF, Liu LS, Wu YH, Liang JY, Jiang C*. Dual Functional Peptide-Driven Nanoparticles for Highly Efficient Glioma-Targeting and Drug Codelivery. Molecular Pharmaceutics. 2016;13(5):1599-1607.
https://pubs.acs.org/doi/full/10.1021/acs.molpharmaceut.6b00051
81. An S, He DS, Wagner E*, Jiang C*, Peptide-like polymers exerting effective glioma-targeted siRNA delivery and release for therapeutic application. Small. 2015;11(38):5142-5150.
https://onlinelibrary.wiley.com/doi/full/10.1002/smll.201501167
82. Cai KM, He X, Song ZY, Yin Q, Zhang YF, Uckun FM, Jiang C*, Cheng JJ*. Dimeric drug polymeric nanoparticles with exceptionally high drug loading and quantitative loading efficiency. Journal of the American Chemical Society. 2015;137(10):3458-3461.
https://pubs.acs.org/doi/full/10.1021/ja513034e
83. An S, Jiang XT, Shi JS, He X, Li JF, Guo YB, Zhang Y, Ma HJ, Lu YF, Jiang C*. Single-component self-assembled RNAi nanoparticles functionalized with tumor-targeting iNGR delivering abundant siRNA for efficient glioma therapy. Biomaterials. 2015;53:330-340.
https://www.sciencedirect.com/science/article/pii/S0142961215002148
84. Guo YB, Zhang YJ, Li JF, Zhang Y, Lu YF, Jiang XT, He X, Ma HJ, An S, Jiang C*. Cell Microenvironment-Controlled Antitumor Drug Releasing-Nanomicelles for GLUT1-Targeting Hepatocellular Carcinoma Therapy. ACS Applied Materials & Interfaces. 2015;7(9):5444-5453.
https://pubs.acs.org/doi/full/10.1021/am5091462
85. Shao K, Ding N, Huang SX, Ren SM, Zhang Y, Kuang YY, Guo YB, Ma HJ, An S, Li YX, Jiang C*. Smart Nanodevice Combined Tumor-Specific Vector with Cellular Microenvironment-Triggered Property for Highly Effective Antiglioma Therapy. ACS Nano. 2014;8(2):1191-1203.
https://pubs.acs.org/doi/full/10.1021/nn406285x
86. Han L, Liu MM, Ye DY, Zhang N, Lim Ed, Lu J, Jiang C*. Tumor cell membrane-targeting pH-dependent electron donor-acceptor fluorescence systems with low background signals. Biomaterials.2014;35(9):2952-2960.
https://www.sciencedirect.com/science/article/pii/S0142961213015044
87. Li JF, Guo YB, Kuang YY, An S, Ma HJ, Jiang C*. Choline-derivate modified co-delivery system for Glioma therapy. Biomaterials. 2013;34(36):9142-9148.
https://www.sciencedirect.com/science/article/pii/S0142961213009782
88. An S, Kuang YY, Li JF, Ma HJ, Guo YB, He X, Jiang C*. Brain-targeting delivery for RNAi neuroprotection against cerebral ischemia reperfusion injury. Biomaterials. 2013;34(35):8949-8959.
https://www.sciencedirect.com/science/article/pii/S0142961213008582
89. Han L, Guo YB, Ma HJ, He X, Kuang YY, Zhang N, Lim Ed, Zhou WJ, Jiang C*. Acid Active Receptor-Specific Peptide Ligand for In Vivo Tumor-Targeted Delivery. Small. 2013;9(21):3647-3658.
https://onlinelibrary.wiley.com/doi/full/10.1002/smll.201300279
90. Huang SX, Shao K, Liu Y, Kuang YY, Li JF, An S, Guo YB, Ma HJ, Jiang C*, Tumor Targeting and Microenvironment Responsive Smart Nanoparticles for Combination Therapy of Anti-Angiogenesis and Apoptosis. ACS Nano. 2013;7(3):2860-2871.
https://pubs.acs.org/doi/full/10.1021/nn400548g
91. Huang SX, Shao K, Kuang YY, Liu Y, Li JF, An S, Guo YB, Ma HJ, He X, Jiang C*. Tumor Targeting and Microenvironment Responsive Smart Nanoparticles for Gene Delivery. Biomaterials. 2013;34(21):5294-5302.
https://www.sciencedirect.com/science/article/pii/S0142961213003530
92. Liu Y, Hu YZ, Guo YB, Ma HJ, Li JF, Jiang C*. Targeted imaging of activated caspase-3 in the central nervous system by a dual functional nano-device. Journal of Controlled Release. 2012;163(2):203-210.
https://www.sciencedirect.com/science/article/pii/S0168365912006578
93. Shao K, Wu JQ, Chen ZQ, Huang SX, Li JF, Ye LY, Lou JN, Zhu LP, Jiang C*. A brain-vectored angiopep-2 based polymeric micelles for the treatment of intracranial fungal infection. Biomaterials. 2012;33(28):6898-6907.
https://www.sciencedirect.com/science/article/pii/S0142961212007004
94. Liu SH, Ma HJ, Guo YB, Li JF, Huang SX, Kuang YY, Han L, Shao K, Liu Y, Jiang C*. Gene and doxorubicin co-delivery system for targeting therapy of glioma. Biomaterials. 2012;33(19):4907-4916.
https://www.sciencedirect.com/science/article/pii/S0142961212003183
95. Li JF, Zhou L, Ye DY, Huang SX, Shao K, Huang RQ, Han L, Liu Y, Ye LY, Lou JN, Jiang C*. Choline-Derivate-Modified Nanoparticles for Brain-Targeting Gene Delivery. Advanced Materials. 2011;23(39):4516-4520.
https://onlinelibrary.wiley.com/doi/full/10.1002/adma.201101899?em_x=22
96. Huang SX, Li JF, Han L, Liu SH, Ma HJ, Huang RQ, Jiang C*, Dual targeting effect of Angiopep-2-modified, DNA-loaded nanoparticles for glioma. Biomaterials. 2011;32(28):6832-6838.
https://www.sciencedirect.com/science/article/pii/S0142961211006351