2026
1. Fan HR, Li XW, Song HL, Zhang SL, Tian ZH,
Chen Y, Zhou ZJ, Geng S, Liu HY, Wang YY, Sun T*, Jiang C*. Size switchable
nanomodulator achieving ratio-precise dual-drug codelivery for synergistic
glutaminevmetabolism modulation in pancreatic cancer. Biomaterials. 2026.124406.
https://www.sciencedirect.com/science/article/pii/S0142961226004308?via%3Dihub
2. Tang WY, Liu B, Liu Y, Wang S, Zhao TC, Wang
JQ*, Jiang C*, Sun T*. AI-Optimized 3D-Printed Dual-Layer Implant: Resolving
Chemo-Immunotherapy Sequential Administration Dilemma for Colorectal Cancer
Peritoneal Metastasis. Advanced Materials. 2026; 0:e73990
https://advanced.onlinelibrary.wiley.com/doi/epdf/10.1002/adma.73990
3. Chen JW, You HY, Huang HF, Chai HH, Zhu RZ,
Guan Y, Tang QS, Li TW, Jiang S, Xu HS, Wang P, Wang Y, Sun MY, Liu BN, Li Z,
Zeng YL, Ping WQ, Teng YL, Yan SL, Li QH, Gu L, Sun T*, Shi ZF*. Biomimetic
Macrophage Cell Membrane-Based Nanoparticles for Effective Treatment of
Glioblastoma Through Boron Neutron Capture Therapy Combined With Immunotherapy. Advanced Science, 2026; 0:e76216.
https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.76216
4. Liu B, Tang WY, Shi MQ, Li FX, Wang Y, Zhao
ZH, Fang MZ, You HY, Sun T, Jiang C*. Reengineered Albumin-Paclitaxel
Nanoparticles Remodeling Tumor Cell Death Pathways for Prevention of
Chemotherapy-Induced Breast Cancer Metastasis. ACS Nano, 2026, 20, 14294-14311
https://doi.org/10.1021/acsnano.6c06136
5. Zhou JT, Su BY, Kang C, Pei YJ, Zhang KK, He
WW, Qi J, You HY, Sun T*, Meng JQ*, Zhu XJ*. Smart Nanodelivery for Eye-Brain
Disorders: Synergistic CCL2 Neutralization and MMP9 Silencing Reverse Anxiety
in High Myopia. Small. 2026; 0:e12276
https://doi.org/10.1002/smll.202512276
6. Chen L, Zhuang ZP, Fan
YX, Jiang C*, Sun T*. Liquid-liquid phase separation
mediated order and pathological chaos: From cellular organization to precision
modulating. Journal of Controlled Release. 2026;390:114516
https://doi.org/10.1016/j.jconrel.2025.114516
2025
7. Zhou JY, Tian ZH, Chen Y, Zhao ZH, Li XW,
Song HL, Fan HR, Wu YX, Wu DX, Geng S,
Liu YC, Sun T*, Jiang C*. Shutting Down the ‘Language
Encoder’: A Pathogen-Derived Nano-Interferer Disrupt Sialylation Metabolism
and Reprogram Intercellular Communication in Glioblastoma. Advanced
Materials. 2025, e16608.
https://advanced.onlinelibrary.wiley.com/doi/full/10.1002/adma.202516608
8. Tian ZH, Chen Y, Zhou JY,
Zhang SL, Fan HR, Li XW, Sun T*, Jiang C*. A Supramolecular Nanoscavengers: based "Cargo-Exchange"
Breaking Cholesterol Metabolic Dysregulation for Glioblastoma Therapy. Advanced
Science. 2025, e19690.
https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202519690
9. Zhou JY, Jiang C*. Targeting Multilayered
Metabolic Networks in Brain Diseases: Emerging Perspectives on Nanodelivery
Strategies. Advanced Science. 2025, e03645.
https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202503645
10. Wang Y, Fan HR, Chen QJ,
Song HL, Li XW, Su BY, Sun T, Cheng LL*, Jiang C*. Mitocytosis-inducing
nanoparticles alleviate gemcitabine resistance via dual disruption of
pyrimidine synthesis and redox homeostasis in pancreatic ductal adenocarcinoma. Biomaterials. 2025;123630.
https://www.sciencedirect.com/science/article/pii/S0142961225005496?dgcid=coauthor
11. Guo Y, You HY, Li YY, Zhou Z, Tian ZH, Jiang
C*, Sun T*. Polymer-engineered PROTAC nanovehicles amplify synergistic effects
with temozolomide by BRD4 degradation. Biomater. Sci. 2025, 13, 5001–5016.
https://pubs.rsc.org/en/content/articlelanding/2025/bm/d5bm00443h
12. Fan HR, Chen HY, Song HL, Li CF, Wang Y,
Zhao ZH, Guo Q, Li XW, Liu MX, Sun T*, Jiang C*. Cascade-Targeted Nanoparticles
for Enhanced Gemcitabine Delivery and Adenosine Metabolism Modulation to
Overcome Treatment Resistance in Pancreatic Cancer. Advanced
Science. 2025, e07118.
https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202507118
13. Li ZM, Xie ZC*, Li YY, Wang C, Tian ZH, Zhao
ZH, Su BY, You HY, Wang JQ*, Sun KY*, Sun T*. Engineered-Macrophage-Escorted
Rotaxane Nanoscavengers for Precise Diquat Detoxification. Advanced
Materials. 2025, 2506466.
https://advanced.onlinelibrary.wiley.com/doi/10.1002/adma.202506466
14. Wang F, You HY, Liu HH, Qi ZR, Shi X, Jin
ZP, Zhong QY, Liu TT, Shen XZ, Sergii Rudiuk, Zhu JM*, Sun T*, Jiang C.
Silencing PTPN2 with nanoparticle-delivered small interfering RNA remodels
tumor microenvironment to sensitize immunotherapy in hepatocellular carcinoma. Acta
Pharmaceutica Sinica B. 2025;15(6):2915-2929.
https://www.sciencedirect.com/science/article/pii/S2211383525001522
15. Zhou Z, Liu MX, You HY, Su BY, Wu YX, Zhang
SL, Sun T, Jiang C*. Multiple-Stimuli-Responsive Biomimetic Polypyrrole
Delivery System for Synergistic Regulation and Restoration of Epileptic Foci. Advanced
Functional Materials. 2025, e10305.
https://advanced.onlinelibrary.wiley.com/doi/10.1002/adfm.202510305
16. Zhang TY, Liu PX, Shen WR, Li C, Zhao ZH, Wu
YX, Sun T, Jiang C*. DNase I-Mediated Chemotactic Nanoparticles for NETs
Targeting and Microenvironment Remodeling Treatment of Acute Ischemic Stroke. Advanced
Science. 2025, e03689.
https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202503689
17. Li XW, Geng S, Chen QJ, Su BY, Song HL, Zhou
JY, Jia R, Fan HR, Li CF, Wang Y, Tian ZH, Sun T, Jiang C*. Disrupting Tumor
Lactate Homeostasis to Sensitize Chemo-Immunotherapy Using a Glucose-Disguised
Lactate Interceptor. ACS Nano. 2025, 19, 21556-21570.
https://pubs.acs.org/doi/10.1021/acsnano.5c03545
18. Guo Y, Fang MZ,
Zhang SL, Zhou Z, Tian ZH, You HY, Chen Y, Zhou JY, Yang XB, Bi YK*, Jiang C*,
Sun T*. PROTAC-loaded nanocapsules degrading BRD4 for radio-chemotherapy
sensitization in glioblastoma. Acta Pharmaceutica Sinica B. 2025;
https://www.sciencedirect.com/science/article/pii/S2211383525001546
19. Zhao ZH, Zhou JY, Li XW, Zhang TY, Tian ZH,
Sun T*, Jiang C*.Manganese-based virus-mimicking nanomedicine with triple
immunomodulatory functions inhibits breast cancer brain metastasis. Biomaterials.
2025;123262.
https://www.sciencedirect.com/science/article/pii/S0142961225001814
20. Fang MZ, Su BY, Zhang SL, Li FX, Guo Yun,
Chen QJ, Wu YX, Liu HY, Jiang C*, Sun T*. Engineered Intelligent
Microenvironment Responsive Prodrug Conjugates Navigated by Bioinspired
Lipoproteins for Reversing Liver Fibrosis. Small Methods. 2025, 2402247.
https://onlinelibrary.wiley.com/doi/10.1002/smtd.202402247
21. You HY, Zhang SL, Zhang YW, Chen QJ, Wu YX,
Zhou Z, Zhao ZH, Su BY, Li XW, Guo Y, Chen Y, Tang WY, Liu B, Fan HR, Geng S,
Fang MZ, Li FX, Liu GN, Jiang C*, Sun T*. Engineered Bacterial Outer Membrane
Vesicles-Based Doxorubicin and CD47-siRNA Co-Delivery Nanoplatform Overcomes
Immune Resistance to Potentiate the Immunotherapy of Glioblastoma. Advanced
Materials. 2025, 2418053.
https://advanced.onlinelibrary.wiley.com/doi/full/10.1002/adma.202418053
22. Su BY, Chen QJ, Li XW, Fang MZ, Wang Y, Song
HL, You HY, Zhou Z, Wu YX, Zhao ZH, Chen Y, Fan HR, Li CF, Jiang C*, Sun T*. A
Methionine Allocation Nanoregulator for the Suppression of Cancer Stem Cells
and Support to the Immune Cells by Epigenetic Regulation. Advanced Science. 2025, 2415207.
https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202415207
23. Zhang SL, You HY, Fan HR, Chen Y, Song HL,
Zhao ZH, Chen QJ, Wang Y, Tian ZH, Wu YX, Zhou Z, Guo Y, Su BY, Li XW, Jia R,
Fang MZ, Jiang C*, Sun T*. Transcytosis-Triggering Nanoparticles for Overcoming
Stromal Barriers and Reversing Immunosuppression in Pancreatic Cancer
Combinatorial Therapy. Nano Letters. 2025;25(7):2949–2959
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24. Li YY, Wu YK, Gao SH, Sun T*, Jiang C*.
PROTAC delivery in tumor immunotherapy: Where are we and where are we going? Journal
of Controlled Release. 2025;378:116–144
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2024
25. Wang Y, Chen QJ, Luo YF, Qu YQ, Li XW, Song
HL, Li CF, Zhang YW, Sun T, Jiang C*. Metabolic Nanoregulators Induce
Ferroptosis and Change Metabolite Flow to Reverse Immunosuppressive Tumor
Microenvironment. ACS Nano. 2024;18(51):34996–35012.
https://pubs.acs.org/doi/10.1021/acsnano.4c13425
26. Song HL, Chen HY, Chen QJ, Fan HR, Li CF, Wang Y, Zhang SL, Li XW,
Su BY, Sun T, Jiang C*. Size and Charge Dual-Switchable Nanoparticles for
Achieving Chemosensitization and Immune Infiltration against Pancreatic Ductal
Adenocarcinoma. Advanced Functional Materials. 2024, 2411643.
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27. Li CF, Chen QJ, Jiang C*. Intelligent micelles for on-demand drug delivery targeting
extracellular matrix of pancreatic cancer. Journal of Controlled Release.
2024;373:879-889.
https://www.sciencedirect.com/science/article/pii/S0168365924005169?via%3Dihub
28. Liu PX, Zhang TY, Wu YX,
Chen QJ, Sun T, Jiang C*. A Peptide-Drug
Conjugate-Based Nanoplatform for Immunometabolic Activation and In Situ Nerve
Regeneration in Advanced-Stage Alzheimer's Disease. Advanced Materials. 2024;2407829.
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29. You HY, Geng S, Li SK, Imani M, Brambilla D,
Sun T*, Jiang C. Recent advances in biomimetic strategies for the immunotherapy
of glioblastoma. Biomaterials. 2024;122694.
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30. Li XW, Guo Q, Chen QJ, Chu YC, Zhang YW,
Chen HY, Zhao ZH, Wang Y, Luo YF, Li CF, You HY, Song HL, Su BY, Jalili K, Sun
T, Jiang C*. Reconciling the Cooperative–Competitive Patterns among Tumor and
Immune Cells for Triple-Negative Breast Cancer Treatment Using Multimodule
Nanocomplexes. Advanced Materials. 2024;2312219.
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31. Su BY, Li SK, Geng S, Brambilla D, Sun R,
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32. Li XW, Sun T*, Jiang C*. Intelligent Delivery Systems in Tumor Metabolism Regulation:
Exploring the Path Ahead. Advanced Materials. 2024;2309582.
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33. Zhao ZH, Chen Y, Sun T,
Jiang C*. Nanomaterials for brain metastasis. Journal
of Controlled Release. 2024;365:833-847.
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34. Qu YQ, Xu JJ, Zhang T, Chen QJ*, Sun T*,
Jiang C*.Advanced nano-based strategies for mRNA tumor vaccine.Acta
Pharmaceutica Sinica B. 2025;14(1):170-189.
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2023
35. Li C, Wu YX, Chen QJ, Luo YF, Liu PX, Zhou
Z, Zhao ZH, Zhang TY, Su BY, Sun T, Jiang C*. Pleiotropic Microenvironment
Remodeling Micelles for Cerebral Ischemia-Reperfusion Injury Therapy by
Inhibiting Neuronal Ferroptosis and Glial Overactivation. ACS Nano.
2023;17(18):18164-18177.
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36. Zhao ZH, Li CF, Zhang YW, Li C, Chu YC, Li
XW, Liu PX, Chen HY, Wang Y, Su BY, Chen QJ, Sun T, Jiang C*. Nanomaterials
with dual immunomodulatory functions for synergistic therapy of breast cancer
brain metastases. Bioactive Materials. 2023;27:474-487.
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37. Luo YF, Li C, Zhang YW, Liu PX, Chen HY,
Zhao ZH, Wang Y, Zhou Z, Song HL, Su BY, Li CF, Li XW, Zhang TY, You HY, Wu YX,
Tian ZH, Zhang SL, Guo Y, Fan HR, Chen QJ, Jiang C*, Sun T*. Gradient tumor
microenvironment-promoted penetrating micelles for hypoxia relief and
immunosuppression reversion in pancreatic cancer treatment. Acta
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38. Sun T*, Chen QJ, Zhou Z,
Li C, Yu T, Jiang C*. A chemiluminescent reporter
assisted by in-situ neutrophils for imaging O2·- at
inflammatory sites. Journal of Controlled Release.
2023;358:382-397.
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39. Zhou Z, Li KY, Guo Y, Liu
PX, Chen QJ, Fan HR, Sun T, Jiang C*. ROS/Electro
Dual-Reactive Nanogel for Targeting Epileptic Foci to Remodel Aberrant Circuits
and Inflammatory Microenvironment. ACS Nano. 2023;17(8):7847-7864.
https://doi.org/10.1021/acsnano.3c01140
40. Chen HY, Song HL, Luo YF, Li CF, Wang Y, Liu
J, Luo FF, Fan HR, Li XW, Sun T*, Jiang C*. Transcytosis Mediated Deep Tumor
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41. Sun T, Jiang C*. Stimuli-Responsive Drug
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42. Liu PX, Zhang TY, Li C, Zhang YW, Zhou Z,
Zhao ZH, Chen QJ, Sun T, Jiang C*. Bioinspired nanoerythrocytes for metabolic
microenvironment remodeling and long-term prognosis promoting of acute ischemic
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43. Chu YC, Su BY, Luo YF, Li C, Zhang YW, Liu
PX, Chen HY, Maciej S, Jiang C*, Sun T*. Compound Nanoemulsion Combined with
Differentiation/ Cytotoxicity Drugs for Modulating Breast Cancer Stemness. Molecular
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44. Zhang YW, You HY, Zhao ZH, Luo YF, Li C, Liu
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Interfere with Mitochondrial Autophagy and Promote the Elimination of
Glioblastoma. Advanced Functional Materials. 2023;2209216.
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45. Zhou Z, Li KY, Chu YC, Li C, Zhang TY, Liu
PX, Sun T, Jiang C*. ROS-removing nano-medicine for navigating inflammatory
microenvironment to enhance anti-epileptic therapy. Acta Pharmaceutica
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47. Zhao ZH, Zhang YJ, Li C, Li XW, Chu YC, Guo
Q, Zhang YW, Xia WY, Liu PX, Chen HY, Wang Y, Li CF, Sun T, Jiang C*.
Microenvironment-tailored micelles restrain carcinoma-astrocyte crosstalk for
brain metastasis. Journal of Controlled Release. 2022;349:520-532.
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48. Chu YC, Luo YF, Su BY, Li C, Guo Q, Zhang
YW, Liu PX, Chen HY, Zhao ZH, Zhou Z, Wang Y, Jiang C*, Sun T*. A
neutrophil-biomimic platform for eradicating metastatic breast cancer stem-like
cells by redox microenvironment modulation and hypoxia-triggered differentiation
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49. Chen HY, Sun T, Jiang C*. Extracellular vesicle-based macromolecule delivery
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50. Chen HY, Guo Q, Chu YC, Li C, Zhang YW, Liu
PX, Zhao ZH, Wang Y, Luo YF, Zhou Z, Zhang TY, Song HL, Li XW, Li CF, Su BY,
You HY, Sun T, Jiang C*. Smart hypoxia-responsive transformable and
charge-reversible nanoparticles for the deep penetration and tumor
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51. Xia WY, Li C, Chen QJ, Huang JC, Zhao ZH,
Liu PX, Xu K, Li L, Hu FY, Zhang SJ, Sun T, Jiang C*, Zhao C*. Intravenous
route to choroidal neovascularization by macrophage-disguised nanocarriers for
mTOR modulation. Acta Pharmaceutica Sinica B. 2022;12(5):2506-2521.
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56. Zhang YW, You HY, Wang YB, Chen QJ, Chu YC,
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57. Zhou WX, Chen XL, Zhou Y, Shi S, Liang C, Yu
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Bacterial Outer Membrane Vesicles for Macrophage Metabolism Modulation and
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59. Li C, Zhao ZH, Luo YF, Ning TT, Liu PX, Chen
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Zhang TY, Li XW, Song HL, Li CF, Sun T, Jiang C*. Macrophage-Disguised
Manganese Dioxide Nanoparticles for Neuroprotection by Reducing Oxidative
Stress and Modulating Inflammatory Microenvironment in Acute Ischemic
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60. Sun T, Zhang GP, Ning TT, Chen QJ, Chu YC,
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Click-Nucleic-Acid-Containing Codelivery System Inducing Collapse of Cellular
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