Size switchable nanomodulator achieving ratio-precise dual-drug codelivery for s...

Time：2026/7/13 23:31:00

Recently, we have reported a multifunctional co-delivery system with size-switchable and enhanced stroma-penetrating capacities. This delivery system can deliver distinct glutamine metabolic regulators deep into pancreatic ductal adenocarcinoma (PDAC) lesions...

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Size switchable nanomodulator achieving ratio-precise dual-drug codelivery for s...

Time：2026/7/13 23:34:49

Recently, we have reported a multifunctional co-delivery system with size-switchable and enhanced stroma-penetrating capacities. This delivery system can deliver distinct glutamine metabolic regulators deep into pancreatic ductal adenocarcinoma (PDAC) lesions...

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AI-Optimized 3D-Printed Dual-Layer Implant: Resolving Chemo-Immunotherapy Sequen...

Time：2026/7/13 23:08:52

Colorectal cancer peritoneal metastasis (CCPM) poses a significant clinical challenge due to the widespread dissemination of lesions, the difficulty of local treatment and a markedly immunosuppressive microenvironment. Although conventional hyperthermic intra...

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Reengineered Albumin-Paclitaxel Nanoparticles Remodeling Tumor Cell Death Pathwa...

Time：2026/5/7 22:30:57

Triple-negative breast cancer (TNBC) represents a formidable clinical challenge due to its poor prognosis and high metastatic propensity. Although paclitaxel chemotherapy remains a cornerstone of treatment, it can paradoxically promote metastasis by facilitat...

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Shutting Down the ‘Language Encoder’: A Pathogen-Derived Nano-Interferer Disru...

Time：2025/12/3 13:25:00

Aberrant enhancement of terminal sialylation in glioblastoma (GBM) has been established as a critical metabolic determinant for maintaining membrane receptor homeostasis, constructing high-throughput intercellular communication networks, and ultimately promot...

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