ROS-removing nano-medicine for navigating inflammatory microenvironment to enhan...

Time：2022/11/24 10:41:01

As a neurological disorder in the brain, epilepsy is not only associated with abnormal synchronized discharging of neurons, but also inseparable from non-neuronal elements in the altered microenvironment. Anti-epileptic drugs (AEDs) merely focusing on neurona...

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A Triple Therapeutic Strategy with Antiexosomal Iron Efflux for Enhanced Ferropt...

Time：2022/9/12 18:56:09

Recently, our group developed an organic-inorganic hybrid nanodrug delivery system based on modulating the tumor immune microenvironment, proposing a triple therapy with highly effective anti-tumor effects. The article was published in the Small with the titl...

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Microenvironment-tailored micelles restrain carcinoma-astrocyte crosstalk for br...

Time：2022/8/31 22:04:41

Based on the important role of the metastatic microenvironment on the colonization and development of metastatic tumors, our research group developed a microenvironment-regulated micelle to inhibit the crosstalk between brain metastases and astrocytes, an...

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A Neutrophil-Biomimic Platform for Eradicating Metastatic Breast Cancer Stem-lik...

Time：2022/8/1 14:52:40

We developed a neutrophil-biomimic platform that regulates redox balance and hypoxic-triggered differentiation to kill metastatic breast cancer stem cells in tumor hypoxia microenvironment. The related work was published online in Acta Pharmaceutica Sinica B...

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Extracellular vesicle-based macromolecule delivery systems in cancer immunothera...

Time：2022/6/30 20:34:05

Recently, our group reviewed the strategies of using extracellular vesicles to deliver macromolecular drugs in cancer immunotherapy. The content was published online in Journal of Controlled Release under the title of “Extracellular vesicle-based macromolecu...

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