ROS/Electro Dual-Reactive Nanogel for Targeting Epileptic Foci to Remodel Aberra...

Time：2023/4/13 16:27:00

We have recently reported a hydrogel nanoparticle drug delivery system, or namely nanogel, which is hopeful to address several problems facing the currently prevalent anti-epileptic drug therapies in epileptic treatment. A reactive oxygen species-res...

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Transcytosis Mediated Deep Tumor Penetration for Enhanced Chemotherapy and Immun...

Time：2023/4/7 15:56:33

Recently, our group has developed a versatile drug delivery system that can trigger transcytosis. The delivery system can efficiently deliver chemotherapy drugs to the deep tumor, regulate the microenvironment, and activate the anti-PDAC immune response. The ...

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Stimuli-Responsive Drug Delivery Systems Triggered by Intracellular or Subcellul...

Time：2023/3/11 13:23:44

Drug delivery systems (DDSs) triggered by local microenvironment represents the state-of-art of nanomedicine design, where the triggering hallmarks at intracellular and subcellular levels could be employed to exquisitely recognize the diseased sites, reduce s...

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Bioinspired nanoerythrocytes for metabolic microenvironment remodeling and long-...

Time：2023/3/8 9:05:06

Recently, our group has developed a nanoerythrocyte, which could regulae the metabolic microenvironment of the brain lesion area and was applied for the whole process of acute ischemic stroke (AIS) treatment. Recently, related article was published online in ...

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Transformable “tubulin traps” interfere with mitochondrial autophagy and promo...

Time：2022/12/6 13:59:24

Based on the important role of protective autophagy in tumor drug resistance of glioblastoma, our research group developed a deformable nano drug delivery system with biomimetic neurofilament functional structure and proposed a combined therapy based on apopt...

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