Nanomaterials for brain metastasis

Time：2023/12/18 14:14:36

Tumor metastasis is a significant contributor to the mortality of cancer patients. Specifically, current conventional treatments are unable to achieve complete remission of brain metastasis. This is due to the unique pathological environment of brain metastasi...

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Pleiotropic Microenvironment Remodeling Micelles for Cerebral Ischemia-Reperfusi...

Time：2023/9/24 16:39:31

Reperfusion injury presents a significant obstacle to neuronal survival following successful recanalization in ischemic stroke, which is characterized by intricate pathophysiological processes comprising numerous interconnected pathways. Oxidative stress-indu...

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Nanomaterials with dual immunomodulatory functions for synergistic therapy of br...

Time：2023/6/28 15:08:20

A long-standing paucity of effective therapies results in the poor outcomes of triple-negative breast cancer brain metastases. Immunotherapy has made progress in the treatment of tumors, but limited by the non-immunogenicity of tumors and strong immunosuppres...

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Gradient Tumor Microenvironment-Promoted Penetrating Micelles for Hypoxia Relief...

Time：2023/6/14 23:35:59

Recently, we developed a hypoxia-responsive nanomicellar drug delivery system for pancreatic cancer microenvironment, which can respond to the hypoxic microenvironment of pancreatic tumors and enhance the penetration of the material into the internal tumor wh...

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ROS/Electro Dual-Reactive Nanogel for Targeting Epileptic Foci to Remodel Aberra...

Time：2023/4/13 16:27:00

We have recently reported a hydrogel nanoparticle drug delivery system, or namely nanogel, which is hopeful to address several problems facing the currently prevalent anti-epileptic drug therapies in epileptic treatment. A reactive oxygen species-res...

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